Canterbury DHB

Context

Post-transplant lymphoproliferative disorders (PTLD)

The post-transplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of neoplasms that are one of the most serious complications of bone marrow and solid organ transplants. Because these disorders are rare, there are no randomized trials from which to derive optimal treatment. Management can be challenging and must balance the goal of PTLD eradication with the risks of graft rejection, graft-versus-host disease, further delays in immune reconstitution and life-threatening infections, among others.

Further reading

DeStefano CB, Desai SH, Shenoy AG, Catlett JP. Management of post-transplant lymphoproliferative disorders. British Journal of Haematology 2018;182(3):330-343. DOI: doi:10.1111/bjh.15263.

About this Canterbury DHB document (950531):

Document Owner:

Not assigned (see Who's Who)

Last Reviewed:

December 2021

Next Review:

December 2024

Keywords:

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Topic Code: 950531