Canterbury DHB

Context

Donor Selection Assessment and Consent

In This Section

Selection of the Donor

Donor Assessment for Allograft - Standard or RIC

Donor Consent

Donor Follow-up

If the Donor is a Minor or a Mentally Incompetent Adult

Selection of the Donor

Selection Criteria

Procedure

  1. Patient contacted to obtain sibling details. Request that they contact all siblings and obtain their consent before forwarding details to the SCT Coordinator.
  2. All siblings are contacted, their details are checked, and they are informed about tissue typing blood tests.
  3. Tissue typing forms are completed and sent to siblings along with the tissue typing information leaflet.
  4. Donor tissue typing results are relayed to the donor first and are only divulged to a third party (eg potential recipient/other family members) after permission has been obtained from the donor.
  5. Non-compatible siblings informed and may be invited to join NZBMDR.

Donor Assessment for Allograft - Standard or RIC

  1. Meeting with SCT Coordinator to discuss harvest procedure.
  2. The potential donor requires a medical history and examination by an “independent” consultant to assess their suitability.
  3. Normal allogeneic donors are encouraged to be immunised with the current recommended influenza vaccine in the one month prior to stem cell donation.
  4. Laboratory tests required pre donation - many of these will already have been done (e.g. tissue typing):
  5. Check whether MRSA swabs are needed. See the CDHB Guidelines for the Control of Multidrug Resistant Organisms.
  6. Consider whether a chest X-ray is likely to alter management after taking into consideration the patient's age, cardiac risk, and clinical findings. Age by itself is not an indication for CXR.

    Note: Bone Marrow Harvest is classified as a low risk procedure.

  7. Venous assessment and consent by NZBS for apheresis procedure.
  8. The donor must sign the consent form for bone marrow procurement prior to the initiation of the SCT conditioning.

Donor Consent

Bone Marrow Harvest

The Schedule for Allogeneic Harvest must be completed.

Donor Follow-up

If the Donor is a Minor or a Mentally Incompetent Adult

There has been much discussion in the literature about the ethics of using children as bone marrow donors. The debate seems to centre on two issues, the determination of whether or not the procedure is in the best interests of the donor, and from whom the consent should be derived. Much of the literature concludes that the psychological benefits to the child outweigh the physical disadvantages of the procedure.

To safeguard the rights of these children, Mumford proposes the following guidelines:

No child may be a donor unless:

For the full article, see Mumford, BJH, 1998.

About this Canterbury DHB document (8899):

Document Owner:

Andrew Butler (see Who's Who)

Issue Date:

December 2016

Next Review:

December 2018

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 8899