Canterbury DHB

Context

Systemic Mastocytosis (SM)

The majority of adults have indolent systemic mastocytosis (ISM) with no evidence of organ involvement. Some may have severe symptoms due to mast cell mediator release.

Aggressive SM is associated with systemic symptoms such as:

May see enlarged lymph nodes, liver, and spleen on examination.

Organ infiltration is referred to as C-findings.

See Pardanani A (2005),4 table 4.

About this Canterbury DHB document (8063):

Document Owner:

Sean Macpherson (see Who's Who)

Issue Date:

August 2018

Next Review:

April 2021

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 8063