Canterbury DHB
This too is a large and complex area. Patients with abnormal haemoglobins present in many different ways.
Because thalassaemia and many abnormal haemoglobins (e.g. Hb S, C, E) occur in similar areas, i.e. the tropics and subtropics, many combinations of defects may arise leading to a variable clinical expression and degree of anaemia.
Sickle cell disease is the most common and most severe of these conditions. For review of sickle cell disease see ASH EPB 2005 pages 51-73 and for a review of sickle cell anaemia treatment see ASH EPB 2005 pages 58-65.
Topic Code: 7950