
Standard Risk (<1% risk TLS)
- CLL with a WBC ≤50 X 109/L
- Multiple myeloma
- CML
- Intermediate-grade NHL and normal serum LDH
Prophylaxis:
- Allopurinol not absolutely necessary but can be given.
- Adequate oral fluid intake, 3 L/day for initial treatment
Note: Alkalinisation of the urine is not currently recommended for TLS.
Topic Code: 6620