Canterbury DHB

Context

MGUS

“M Proteins” (Monoclonal Immunoglobulins or "Paraproteins") are common, occurring in over 5% of people aged >70 years (Kyle et al, 2002). M proteins are found in several abnormal situations including:

The frequency of the different types of monoclonal protein in MGUS are: IgG 69%, IgM 17% and IgA 11%. Monoclonal light chains are seen in the urine of 31% of people with MGUS (Kyle 2002) and it is possible to have “light chain only” MGUS. Other immunoglobulin subtypes are rare in MGUS.

In This Section

Assessment of M proteins

Low Risk MGUS

Higher Risk MGUS

MGUS Prognosis

Management of MGUS - Information for general practitioners

About this Canterbury DHB document (6469):

Document Owner:

Sean Macpherson (see Who's Who)

Issue Date:

September 2014

Next Review:

September 2016

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 6469