Canterbury DHB



“M Proteins” (Monoclonal Immunoglobulins or "Paraproteins") are common, occurring in over 5% of people aged >70 years (Kyle et al, 2002). M proteins are found in several abnormal situations including:

The frequency of the different types of monoclonal protein in MGUS are: IgG 69%, IgM 17% and IgA 11%. Monoclonal light chains are seen in the urine of 31% of people with MGUS (Kyle 2002) and it is possible to have “light chain only” MGUS. Other immunoglobulin subtypes are rare in MGUS.

In This Section

Assessment of M proteins

Low Risk MGUS

Higher Risk MGUS

MGUS Prognosis

Management of MGUS - Information for general practitioners

About this Canterbury DHB document (6469):

Document Owner:

Amy Holmes (see Who's Who)

Last Reviewed:

September 2014

Next Review:

September 2016


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Topic Code: 6469