Canterbury DHB
“M Proteins” (Monoclonal Immunoglobulins or "Paraproteins") are common, occurring in over 5% of people aged >70 years (Kyle et al, 2002). M proteins are found in several abnormal situations including:
The frequency of the different types of monoclonal protein in MGUS are: IgG 69%, IgM 17% and IgA 11%. Monoclonal light chains are seen in the urine of 31% of people with MGUS (Kyle 2002) and it is possible to have “light chain only” MGUS. Other immunoglobulin subtypes are rare in MGUS.
Topic Code: 6469