Canterbury DHB

Context

Essential Thrombocythaemia (ET)

Essential thrombocythaemia (ET) is the commonest MPN, and is predominantly characterised by excessive clonal megakaryocyte production and thrombocytosis.

Most cases occur in people aged between 50–60 years, although it can occur in young adults.

Fifty per cent of patients are asymptomatic, and are diagnosed following a routine FBC check.

The other 50% present with either:

Patients with constitutional symptoms and splenomegaly are more likely to have fibrotic changes on trephine.

Of ET patients:

In This Section

Diagnostic Criteria

Management

Referral to GP for Shared Care

Hydroxyurea-Refractory and -Intolerant ET

Long-term Outcomes in ET and Management of Transformation

Further Reading

About this Canterbury DHB document (6233):

Document Owner:

Sean Macpherson (see Who's Who)

Issue Date:

August 2018

Next Review:

April 2021

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 6233