Canterbury DHB

Context

Potential New Case of Haemophilia

Newborn males

  1. Take blood from umbilical cord (or peripheral vein) for factor level.
  2. If factor assay indicates severe (<1%) or moderate (1 - 4%) factor VIII/IX deficiency it is essential that the results are sensitively communicated to the parents by experienced staff.
  3. Confirm diagnosis with a further factor level.
  4. Follow newborn closely for a minimum of 7 days after birth through daily phone contact from Haemophilia Centre or GP and frequent midwife visits. Educate parents regarding symptoms of ICH - poor feeding, irritability, listlessness, full fontanelle, convulsions, pallor, etc.

    Recommended imaging:

  5. If confirmed ICH, treat according to National Guidelines for intracranial haemorrhage.

Newborn females

Suggest factor VIII/IX level is measured on females born to carrier mothers to detect the occasional carrier female with low levels at risk of symptomatic bleeding.

Newborns with prolonged APTT but no family history

Assay factor VIII/IX levels in newborns without a family history of haemophilia if coagulation screen shows prolonged APTT, particularly:

About this Canterbury DHB document (5274):

Document Owner:

Mark Smith (see Who's Who)

Issue Date:

August 2016

Next Review:

August 2019

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 5274