Canterbury DHB


Chronic Knee Synovitis

Medical management should be used initially but if there is a failure to respond within 10 - 12 weeks arthroscopic synovectomy or radionuclide synovectomy should be considered. A treatment plan should be developed in consultation with the relevant specialists.

Treatment Regimen

FVIII 15 - 20 u/kg daily or FIX 20 - 30 u/kg daily for two weeks then review

Ongoing intensive treatment daily to three times weekly as required.


Prednisone 1 mg/kg 5 days


Night splinting to immobilise ; day splints to protect joint


Isometric exercises of adjacent muscles

Endpoint: Continue up to three months. In non-response, do not continue beyond three months and consider alternative management.

About this Canterbury DHB document (5256):

Document Owner:

Mark Smith (see Who's Who)

Issue Date:

August 2016

Next Review:

August 2019


Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 5256