Canterbury DHB


Chronic Knee Synovitis

Use medical management first, but if there is a failure to respond within 10 to 12 weeks, consider arthroscopic synovectomy or radionuclide synovectomy. Develop a treatment plan in consultation with the relevant specialists.

Treatment Regimen

FVIII 15 to 20 u/kg daily or FIX 20 to 30 u/kg daily for two weeks then review.

Ongoing intensive treatment daily to three times weekly as required.


Prednisone 1 mg/kg 5 days


Night splinting to immobilise ; day splints to protect joint


Isometric exercises of adjacent muscles

Endpoint: Continue up to three months. In non-response, do not continue beyond three months and consider alternative management.

About this Canterbury DHB document (5256):

Document Owner:

Sean Macpherson (see Who's Who)

Last Reviewed:

November 2019

Next Review:

November 2022


Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document. Disclaimer

Topic Code: 5256