Canterbury DHB
Note: Discuss all surgery with regional haematologist and individualise treatment. Refer liver or renal biopsy to regional haemophilia services.
Aim: To increase factor level to 50%.This is most easily achieved with a multiple dose schedule. Combine with an antifibrinolytic therapy.
Treatment Regimen |
FVIII 25 to 30 u/kg, repeat dose at 24 hours and as required. |
FIX 50 u/kg, repeat dose at 24 hours and as required. |
Tranexamic acid 1 g three times a day, 7 to 14 days. Topical agents as required. |
Consultation between blood centre, surgeon, and haematologist is essential.
Prepare a written management protocol.
Ensure appropriate target levels by factor-level monitoring.
Aim: To increase factor level to a target of 80 to 100% with trough level > 50%.
Topic Code: 5246