Canterbury DHB
The most common clinical conditions which may be complicated by DIC are as follows:
Generally, treating the primary disease is the most effective treatment for DIC. For example, antibiotics, delivery of baby, or in the case of APML, All Trans Retinoic Acid. If bleeding is a problem, replacement of the depleted factors is recommended. In practice, this would usually be either platelets, and /or cryoprecipitate, and/or fresh frozen plasma. Cryoprecipitate provides fibrinogen and factor VIII. There is a pure lypholised fibrinogen concretrate (haemocomplettan-P or Riastap) available from Blood Bank, I g per vial.
Topic Code: 5218