Canterbury DHB

Context

Outline of Treatment for Severe AA

Note: It is important to monitor the blood counts closely for any sign of improvement while organising a stem cell transplant or immunosupression. Spontaneous recovery of bone marrow function may occur even in severely affected patients.

The following image shows how to treat acquired severe aplastic anaemia. HSCT may be considered for patients aged 35-50 who fail to respond to first line immunosuppressive therapy. This requires a matched sibling donor or a suitably matched unrelated donor if no matched sibling donor is available. (Sureda et al 2015). ATG, antithymocyte globulin; HLA, human leucocyte antigen; HSCT, haemopiietic stem cell transplantation; CSA, ciclopsporin.

EBMT flowchart

About this Canterbury DHB document (4927):

Document Owner:

Not assigned (see Who's Who)

Issue Date:

August 2017

Next Review:

August 2019

Keywords:

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Topic Code: 4927