Canterbury DHB
Note: Monitor the blood counts closely for any sign of improvement while organising a stem cell transplant or immunosupression. Spontaneous recovery of bone marrow function may occur even in severely affected patients.
The following image shows how to treat acquired severe aplastic anaemia. HSCT may be considered for patients aged 35 to 50 years who fail to respond to first line immunosuppressive therapy. This requires a matched sibling donor or a suitably matched unrelated donor if no matched sibling donor is available. (Sureda et al 2015). ATG, antithymocyte globulin; HLA, human leucocyte antigen; HSCT, haemopoietic stem cell transplantation; CSA, ciclopsporin.
Topic Code: 4927