Canterbury DHB
The disease usually presents with a relatively short history. The following signs all reflect a failure of normal blood cell production:
In addition, leukaemic cell infiltration may produce:
CNS involvement can occur, but it is rare. AML may occur at any age but it is most common in the elderly. The median age at presentation is about 68 and therefore over half of new patients with AML will be over 60. See MA Sekeres - ASH EPB, 2004, pp 109 - 114.
Topic Code: 4273